Description

1-Indolizinol, Octahydro-6,7,8-Tris(Methoxymethoxy)-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined indolizidine alkaloid derivative, serving as a critical chiral building block and synthetic intermediate. Its value lies in its functionalized polycyclic structure, which provides a versatile scaffold for constructing complex molecules with high stereochemical fidelity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active ingredients, chiral catalysts, or exploring new chemical entities in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of potential drug candidates, especially those targeting neurological or infectious diseases.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides due to its complex alkaloid backbone.
• Asymmetric Catalysis: Serves as a ligand or a core structure for designing new chiral catalysts in stereoselective synthesis.
• Medicinal Chemistry: Employed as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Natural Product Synthesis: A valuable intermediate for the total or semi-synthesis of complex indolizidine and related alkaloids.
• Chemical Biology: Used as a molecular probe to study biological pathways and enzyme interactions.

Basic Information

Product Name	1-Indolizinol, Octahydro-6,7,8-Tris(Methoxymethoxy)-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156198-82-2
Molecular Formula	C14H27NO6
Molecular Weight	305.37 g/mol
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-6,7,8-tris(methoxymethoxy)indolizine-1-ol; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-6,7,8-tris(methoxymethoxy)-1-indolizinol; Tris-MOM-protected indolizidinol; Indolizidine-triol tris-MOM ether; 1-Indolizinol, octahydro-6,7,8-tris(methoxymethoxy)-, (1S,6R,7S,8R,8aR)-; 156198-82-2
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to verify the stereochemical integrity and chemical purity, meeting the exacting standards required for pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.