Description

Bicyclo[3.1.0]Hexan-3-One, 2-(1-Hydroxyethylidene)-6,6-Dimethyl-, (1S,5R)- is a high-purity, chiral bicyclic ketone derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block for the construction of complex molecular architectures, particularly in the pharmaceutical sector. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, including potential antiviral, anti-inflammatory, or central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of novel, high-efficacy pesticides and herbicides where its unique bicyclic structure imparts specific biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric hydrogenation and other enantioselective transformations.
• Fragrance and Flavor Chemistry: Potential intermediate for creating novel synthetic musk compounds or other complex odorants due to its rigid, functionalized ketone structure.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing polymers with specific thermal or mechanical properties.
• Academic and R&D Laboratories: Employed in methodological studies and the total synthesis of natural products featuring bicyclo[3.1.0]hexane skeletons.

Basic Information

Item	Detail
Product Name	Bicyclo[3.1.0]Hexan-3-One, 2-(1-Hydroxyethylidene)-6,6-Dimethyl-, (1S,5R)-
CAS No.	156145-74-3
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(1S,5R)-2-(1-Hydroxyethylidene)-6,6-dimethylbicyclo[3.1.0]hexan-3-one; (1S,5R)-2-Acetyl-6,6-dimethylbicyclo[3.1.0]hexan-3-one hydrate (tautomer); 2-(1-Hydroxyethylidene)-6,6-dimethylbicyclo[3.1.0]hexan-3-one, (1S,5R)-; Chiral Bicyclo[3.1.0]hexanone derivative; (1S,5R)-HAB (abbreviation); (1S,5R)-enantiomer of 156145-74-3
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.1.0]Hexan-3-One, 2-(1-Hydroxyethylidene)-6,6-Dimethyl-, (1S,5R)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, GC for residual solvents, and NMR/IR for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent any potential degradation or contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (1S,5R)-enantiomer
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.