Description

Dimadectin is a high-purity macrocyclic lactone compound, widely recognized for its potent anthelmintic and acaricidal properties. Its primary value lies in its efficacy against a broad spectrum of internal and external parasites, making it a critical active pharmaceutical ingredient (API) in veterinary medicine. This compound is essential for manufacturers developing formulations for livestock, companion animals, and agricultural applications to ensure animal health and productivity.

Application

• As an active pharmaceutical ingredient (API) in veterinary injectable, pour-on, and oral formulations.
• For the control and treatment of nematode and arthropod parasites in cattle, swine, sheep, and goats.
• In the development of parasiticides for companion animals, including dogs and cats.
• As a key component in agricultural and livestock pest management programs.
• For use in research and development of new antiparasitic agents and combination therapies.
• In the manufacturing of medicated premixes for feed additives.

Basic Information

Product Name	Dimadectin
CAS No.	156131-91-8
Molecular Formula	C₃₃H₄₈O₇
Molecular Weight	556.73 g/mol
Synonyms	Dimadectin; 4"-Deoxy-4"-epi-methylaminoavermectin B1; 4"-Deoxy-4"-epi-(N-methylamino)avermectin B1; MK-243; LL-F28249-α; 5-O-Demethyl-28-deoxy-6,28-epoxy-25-(1-methylpropyl)ivermectin B1a; (10E,14E,16E)-(1R,4S,5'S,6R,6'R,8R,12R,13S,20R,21R,24S)-6'-[(S)-sec-butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-3,7,19-trioxo-2-oxa-18-azatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our Dimadectin is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to guarantee purity and consistency. Certificates of Analysis (COA) documenting full compliance with agreed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.