Description

(E)-2,10-Dimethyl-4-(4-Methylpiperazin-1-Yl)-10H-Benzo[B]Thieno[2,3-E][1,4]Diazepine is a high-purity, complex heterocyclic compound featuring a benzothienodiazepine core structure, which is of significant interest in advanced pharmaceutical research and development. Its molecular architecture, incorporating a piperazine moiety, makes it a valuable pharmacological intermediate for the synthesis of novel therapeutic agents. This compound is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in developing new drug candidates, particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological assays to study specific receptor interactions.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, target-specific molecules in custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Item	Details
Product Name	(E)-2,10-Dimethyl-4-(4-Methylpiperazin-1-Yl)-10H-Benzo[B]Thieno[2,3-E][1,4]Diazepine
CAS No.	155817-84-8
Molecular Formula	C20H22N4S
Molecular Weight	350.48 g/mol
Synonyms	Olanzapine Impurity F; (E)-Olanzapine; (E)-2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine; LY170053 (E-isomer); Zyprexa Related Compound F; trans-Olanzapine; Benzo[b]thieno[2,3-e][1,4]diazepine, 2,10-dimethyl-4-(4-methyl-1-piperazinyl)-, (E)-; 4-(4-Methylpiperazin-1-yl)-2,10-dimethyl-10H-benzo[b]thieno[2,3-e][1,4]diazepine
EINECS	Contact for details

Quality Control

Every batch of our (E)-2,10-Dimethyl-4-(4-Methylpiperazin-1-Yl)-10H-Benzo[B]Thieno[2,3-E][1,4]Diazepine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.