Description

1-Bromobut-3-En-2-One is a versatile and highly reactive brominated α,β-unsaturated ketone, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both an electrophilic bromine atom and a Michael acceptor site for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to introduce key functional groups and create novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of various active pharmaceutical ingredients (APIs), particularly those containing heterocyclic cores like pyrazoles, isoxazoles, and thiazoles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create bioactive molecules.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, such as cycloadditions and nucleophilic substitutions.
• Ligand and Catalyst Synthesis: Useful for constructing complex organic ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Integral to the multi-step synthesis of dyes, flavors, and fragrances requiring specific bromo-ketone functionalities.

Basic Information

Product Name	1-Bromobut-3-En-2-One
CAS No.	155622-69-8
Molecular Formula	C₄H₅BrO
Molecular Weight	149.00 g/mol
Synonyms	3-Buten-2-one, 1-bromo-; 1-Bromo-3-buten-2-one; 4-Bromobut-3-en-2-one; 3-Bromo-3-buten-2-one; Bromovinyl methyl ketone; (Bromomethyl)vinyl ketone; 1-Bromobut-3-en-2-one; 4-Bromo-3-buten-2-one
EINECS	Contact for details

Quality Control

Our 1-Bromobut-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Clear to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.