Description

5-Fluoro-2-Mercaptobenzothiazole is a fluorinated derivative of the versatile benzothiazole heterocycle, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity, where the fluorine substituent and the mercapto group enable precise modifications to create high-performance materials and active pharmaceutical ingredients. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Polymer Additives: Acts as a modifying agent or chain-transfer agent in the production of specialty polymers and rubber vulcanization accelerators.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and fluorescent dyes due to its electron-withdrawing characteristics.
• Chemical Synthesis Reagent: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.

Basic Information

Product Name	5-Fluoro-2-Mercaptobenzothiazole
CAS No.	155559-81-2
Molecular Formula	C7H4FN1S2
Molecular Weight	185.24 g/mol
Synonyms	5-Fluoro-2-benzothiazolethiol; 5-Fluoro-2-mercapto-1,3-benzothiazole; 2-Mercapto-5-fluorobenzothiazole; 5-Fluoro-2-sulfanylbenzothiazole; 5-Fluoro-2-benzothiazolinethione; 5-Fluoro-1,3-benzothiazole-2-thiol; FMBT; 155559-81-2
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Mercaptobenzothiazole is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support compliance with global regulatory frameworks, and specifications can be aligned with cGMP, ICH Q7, and other relevant pharmaceutical or industrial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and easily oxidized; prolonged exposure to air and light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.