Description

Dihydroetorphine Hydrochloride is a potent semi-synthetic opioid analgesic compound. This high-purity active pharmaceutical ingredient (API) is critical for advanced pharmaceutical research and development, particularly in the study of pain management and receptor pharmacology. It is primarily utilized by pharmaceutical manufacturers, research institutions, and analytical laboratories requiring a reliable and consistent supply of this specialized chemical.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the development of novel analgesic drugs and central nervous system (CNS) targeting therapies.
• Analytical Reference Standard: Used in high-performance liquid chromatography (HPLC), mass spectrometry (MS), and other analytical methods for method development, validation, and quality control testing.
• Biochemical & Pharmacological Studies: Employed in in vitro and in vivo studies to investigate opioid receptor binding, signal transduction pathways, and the mechanisms of analgesia.
• Controlled Substance Analysis: Serves as a certified reference material (CRM) for forensic and toxicology laboratories in the identification and quantification of related substances.
• Academic Research: Utilized in university and institutional research projects focused on neurochemistry, addiction science, and pain physiology.

Basic Information

Product Name	Dihydroetorphine Hydrochloride
CAS No.	155536-45-1
Molecular Formula	C₂₅H₃₃NO₄ • HCl
Molecular Weight	448.00 g/mol (approx.)
Synonyms	DHM-99; DHE; 7,8-Dihydroetorphine Hydrochloride; 4,5α-Epoxy-3-hydroxy-6-methoxy-α,17-dimethyl-α-propyl-6,14-ethenomorphinan-7-methanol Hydrochloride; 18,19-Dihydroetorphine HCl; (5α,7α)-4,5-Epoxy-3-hydroxy-6-methoxy-α,17-dimethyl-α-propyl-6,14-ethenomorphinan-7-methanol Hydrochloride
EINECS	Contact for details

Quality Control

Our Dihydroetorphine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, HPLC), assay (HPLC), and tests for related substances and residual solvents, to ensure it meets stringent purity standards suitable for research and development. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.