Description

Dl-2-Boc-7-(Ethyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block and key intermediate in the development of complex pharmaceutical molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Peptidomimetic Chemistry: Used to incorporate constrained, non-natural amino acid motifs into peptide backbones to enhance metabolic stability and biological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing combinatorial libraries and exploring structure-activity relationships (SAR) in drug discovery.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce the tetrahydroisoquinoline moiety into target molecules.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis and the development of new catalytic processes.

Basic Information

Product Name	Dl-2-Boc-7-(Ethyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid
CAS No.	155367-48-9
Molecular Formula	C₁₇H₂₃NO₄
Molecular Weight	305.37 g/mol
Synonyms	DL-2-[(tert-Butoxycarbonyl)amino]-7-ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Ethyl-2-[(tert-butoxycarbonyl)amino]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 2-Boc-amino-7-ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 7-Ethyl-2-N-Boc-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (±)-2-[(tert-Butoxycarbonyl)amino]-7-ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; DL-2-(Boc-amino)-7-ethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; Boc-7-Ethyl-DL-Tic-OH
EINECS	Contact for details

Quality Control

Our Dl-2-Boc-7-(Ethyl)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.