Description

4-(1H-Indol-3-Yl)Piperidine-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-value protected piperidine-indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a reactive scaffold for constructing complex molecules with precise stereochemistry and functional group compatibility. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and explore new chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, serotonin receptors, and other neurological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole moiety's bioactivity.
• Chemical Biology & Proteomics: Serves as a scaffold for designing molecular probes and enzyme inhibitors to study biological processes.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the exploration of novel heterocyclic compounds for therapeutic applications.
• Custom Synthesis & Contract Manufacturing: A high-purity starting material for custom synthesis projects requiring complex, multi-step organic transformations.
• Academic Research: Utilized in universities and research institutes for methodological development in organic synthesis and catalysis.

Basic Information

Product Name	4-(1H-Indol-3-Yl)Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	155302-28-6
Molecular Formula	C18H24N2O2
Molecular Weight	300.40 g/mol
Synonyms	1-Boc-4-(3-indolyl)piperidine; tert-Butyl 4-(1H-indol-3-yl)piperidine-1-carboxylate; 4-(Indol-3-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 4-(1H-Indol-3-yl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(1H-indol-3-yl)piperidine; 4-(3-Indolyl)-1-piperidinecarboxylic acid tert-butyl ester; 4-(1H-Indol-3-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(1H-Indol-3-Yl)Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.