Description

(4R)-2-Methyl-4,5,5-Triphenyl-1,3,2-Oxazaborolidine is a chiral oxazaborolidine derivative that serves as a highly effective organocatalyst. This compound is valued for its ability to induce high enantioselectivity in a variety of organic transformations, particularly in asymmetric synthesis. It is a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to produce optically pure intermediates.

Application

• Asymmetric Catalysis: Employed as a chiral Lewis acid catalyst in enantioselective Diels-Alder, aldol, and reduction reactions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) requiring high optical purity.
• Agrochemical Development: Applied in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Facilitates the synthesis of specialty chemicals, flavors, and fragrances where stereochemistry is crucial.
• Academic & Industrial R&D: A key tool in methodological development for new asymmetric synthetic routes in laboratory and pilot-scale settings.
• Material Science: Potential use in the synthesis of chiral polymers and advanced organic materials with specific optical properties.

Basic Information

Item	Detail
Product Name	(4R)-2-Methyl-4,5,5-Triphenyl-1,3,2-Oxazaborolidine
CAS No.	155268-88-5
Molecular Formula	C26H24BNO
Molecular Weight	377.29 g/mol
Synonyms	(R)-2-Methyl-4,5,5-triphenyl-1,3,2-oxazaborolidine; (4R)-2-Methyl-4,5,5-triphenyl-4,5-dihydro-1H-1,3,2-oxazaborole; Corey's (R)-Oxazaborolidine Catalyst; (R)-Me-CBS; (R)-Methyl-CBS; (R)-2-Methyl-CBS; B-Methyloxazaborolidine
EINECS	Contact for details

Quality Control

Our (4R)-2-Methyl-4,5,5-Triphenyl-1,3,2-Oxazaborolidine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for catalytic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.