Description

4,5,6,7-Tetrafluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-value fluorinated heterocyclic building block, specifically a methyl ester derivative of a tetrafluorobenzothiophene carboxylic acid. This compound is critical for introducing the unique electronic and steric properties of a perfluorinated benzothiophene core into advanced molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as in materials science for the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated benzothiophene moiety enhances biological activity and environmental stability.
• Organic Electronic Materials: Serves as a precursor for organic semiconductors, charge-transport materials, and fluorophores used in OLEDs, OFETs, and solar cells.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile building block for exploratory chemistry in academic and industrial settings to create novel fluorinated compounds.
• Liquid Crystal and Advanced Polymer Synthesis: Incorporated into the backbone of high-performance polymers and liquid crystal materials to modify thermal and optical properties.

Basic Information

Product Name	4,5,6,7-Tetrafluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	155167-42-3
Molecular Formula	C10H4F4O2S
Molecular Weight	264.20 g/mol
Synonyms	Methyl 4,5,6,7-tetrafluoro-1-benzothiophene-2-carboxylate; Methyl 4,5,6,7-tetrafluorobenzo[b]thiophene-2-carboxylate; 4,5,6,7-Tetrafluorobenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Methoxycarbonyl-4,5,6,7-tetrafluorobenzo[b]thiophene; Benzo[b]thiophene-2-carboxylic acid, 4,5,6,7-tetrafluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrafluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory practices for handling fine chemicals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.