Description

1H-Indole-3-Carboxylic Acid,7-(Trifluoromethyl)-,Methyl Ester is a high-value, fluorinated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for synthesis and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe or substrate to study enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke chemicals for client projects.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid,7-(Trifluoromethyl)-,Methyl Ester
CAS No.	155134-38-6
Molecular Formula	C11H8F3NO2
Molecular Weight	243.18 g/mol
Synonyms	Methyl 7-(Trifluoromethyl)-1H-indole-3-carboxylate; 7-(Trifluoromethyl)-1H-indole-3-carboxylic acid methyl ester; 7-Trifluoromethylindole-3-carboxylic Acid Methyl Ester; 1H-Indole-3-carboxylic acid, 7-(trifluoromethyl)-, methyl ester; Methyl 7-trifluoromethylindole-3-carboxylate; 7-Trifluoromethyl-1H-indole-3-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid,7-(Trifluoromethyl)-,Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.