Description

1H-Pyrrole-2,5-Dione, 3-(Hydroxymethyl)-1-Methyl- (9Ci) is a specialized N-substituted maleimide derivative, a versatile building block in advanced organic synthesis. Its molecular structure, featuring both a reactive maleimide core and a hydroxymethyl substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries, particularly for developing active pharmaceutical ingredients (APIs), functional monomers, and cross-linking agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting specific biological pathways where the maleimide group enables selective conjugation.
• Polymer Science & Material Chemistry: Serves as a functional monomer or cross-linker in the production of specialty polymers, resins, and coatings, imparting thermal stability and specific reactivity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic structure.
• Bioconjugation & Probe Development: The maleimide group is widely utilized for selective thiol coupling, making this compound valuable for creating antibody-drug conjugates (ADCs), fluorescent probes, and diagnostic reagents.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D in constructing complex heterocycles and exploring new reaction methodologies.
• Electronic Chemicals: Potential precursor in the synthesis of organic semiconductors or photoactive materials for electronic applications.

Basic Information

Product Name	1H-Pyrrole-2,5-Dione, 3-(Hydroxymethyl)-1-Methyl- (9Ci)
CAS No.	155088-20-3
Molecular Formula	C6H7NO3
Molecular Weight	141.13 g/mol
Synonyms	3-(Hydroxymethyl)-1-methyl-1H-pyrrole-2,5-dione; 1-Methyl-3-(hydroxymethyl)maleimide; N-Methyl-3-(hydroxymethyl)maleimide; 3-Hydroxymethyl-1-methylmaleimide; Maleimide, N-methyl-3-(hydroxymethyl)-; 1-Methyl-3-hydroxymethylpyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2,5-Dione, 3-(Hydroxymethyl)-1-Methyl- (9Ci) is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality system supports development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases, reducing agents, and amines. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.