Description

6-Bromo-4-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates bromine and fluorine substituents on a benzothiophene core, making it a versatile intermediate for constructing complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the benzothiophene scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and functional group transformations due to the reactive bromine and ester groups.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the exploration of new chemical spaces.

Basic Information

Item	Detail
Product Name	6-Bromo-4-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester
CAS No.	154650-60-9
Molecular Formula	C10H6BrFO2S
Molecular Weight	289.12 g/mol
Synonyms	Methyl 6-Bromo-4-fluorobenzo[b]thiophene-2-carboxylate; 6-Bromo-4-fluorobenzo[b]thiophene-2-carboxylic acid methyl ester; 154650-60-9; Benzo[b]thiophene-2-carboxylic acid, 6-bromo-4-fluoro-, methyl ester; Methyl 6-bromo-4-fluoro-1-benzothiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Fluoro-Benzo[B]Thiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.