Description

5-Methyl-4-Bromothiophen-2-Ylboronic Acid is a high-value organoboron building block, specifically a thiophene-substituted boronic acid derivative. Its core value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules in modern synthetic chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, ligand synthesis, and the development of functional organic electronics.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the thiophene moiety for biological activity.
• Material Science & Organic Electronics: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new carbon-carbon bond-forming reactions and creating novel chemical libraries.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Methyl-4-Bromothiophen-2-Ylboronic Acid
CAS No.	154566-69-5
Molecular Formula	C5H6BBrO2S
Molecular Weight	220.88 g/mol
Synonyms	(5-Methyl-4-bromothiophen-2-yl)boronic acid; 4-Bromo-5-methylthiophene-2-boronic acid; 2-Borono-4-bromo-5-methylthiophene; 5-Methyl-4-bromo-2-thienylboronic acid; 154566-69-5; 4-Bromo-5-methyl-2-thienylboronic acid; B-(4-Bromo-5-methyl-2-thienyl)boronic acid
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-Bromothiophen-2-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and during weighing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.