Description

Ethanone, 1-[(1R,2R,4R)-1-Methyl-7-Oxabicyclo[2.2.1]Hept-5-En-2-Yl]-, Rel- is a high-purity, stereochemically defined chiral building block and intermediate of significant value in advanced organic synthesis. Its rigid oxabicyclic structure and specific stereochemistry make it a critical precursor for the development of complex, biologically active molecules. This compound is essential for research and production in the pharmaceutical and fine chemical industries, where precise molecular architecture is required for creating novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and catalysts for enantioselective synthesis, enhancing the efficiency of producing single-enantiomer compounds.
• Natural Product Synthesis: Serves as a building block in the total synthesis of natural products with complex polycyclic or bridged ring systems.
• Agrochemical Research: Employed in the development of new, stereospecific pesticides and herbicides where biological activity is highly dependent on molecular configuration.
• Material Science Monomer: Investigated as a specialty monomer for creating polymers with unique thermal or mechanical properties derived from its rigid bicyclic framework.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing high-value odorants and flavoring agents with specific stereochemical notes.

Basic Information

Product Name	Ethanone, 1-[(1R,2R,4R)-1-Methyl-7-Oxabicyclo[2.2.1]Hept-5-En-2-Yl]-, Rel-
CAS No.	154558-62-0
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	rel-(1R,2R,4R)-1-Methyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl methyl ketone; (1R,2R,4R)-1-Methyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl ethanone; 1-[(1R,2R,4R)-1-Methyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl]ethanone; Chiral Oxanorbornenyl Methyl Ketone; 7-Oxabicyclo[2.2.1]hept-5-ene-2-acetone derivative; (rel)-(1R,2R,4R)-1-Methyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl methyl ketone; Bicyclic Enone Ether Intermediate
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1R,2R,4R)-1-Methyl-7-Oxabicyclo[2.2.1]Hept-5-En-2-Yl]-, Rel- adheres to stringent quality management systems to ensure batch-to-batch consistency and high chemical purity. The material is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy to confirm identity, stereochemical purity (enantiomeric excess), and chemical assay. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.