Description

1-(3,4-Difluorophenyl)-1H-Pyrrole-2,5-Dione is a high-purity, heterocyclic organic compound featuring a maleimide core substituted with a difluorophenyl group. This structure makes it a valuable and versatile pharmaceutical intermediate and chemical building block for advanced synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries to construct complex molecules for new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel small-molecule drugs, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic compounds and exploring new chemical spaces.
• Bioconjugation Reagent: The maleimide group allows for selective conjugation with thiols, useful in biotech applications for labeling and modifying biomolecules.

Basic Information

Product Name	1-(3,4-Difluorophenyl)-1H-Pyrrole-2,5-Dione
CAS No.	154505-91-6
Molecular Formula	C10H5F2NO2
Molecular Weight	209.15 g/mol
Synonyms	1-(3,4-Difluorophenyl)-1H-pyrrole-2,5-dione; 3,4-Difluorophenylmaleimide; 1-(3,4-Difluorophenyl)maleimide; N-(3,4-Difluorophenyl)maleimide; 2,5-Pyrrolidinedione, 1-(3,4-difluorophenyl)-; 154505-91-6; 1H-Pyrrole-2,5-dione, 1-(3,4-difluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-(3,4-Difluorophenyl)-1H-Pyrrole-2,5-Dione is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.