Description

Phenoxy-D5-Acetic Acid CAS NO 154492-74-7 is a high-purity, deuterium-labeled analog of phenoxyacetic acid, where five hydrogen atoms are replaced with deuterium. This isotopic labeling is critical for applications requiring internal standards in mass spectrometry, ensuring precise and accurate quantitative analysis. It is an essential material for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing industries, where tracking and quantification of metabolites or related compounds are paramount.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical and pharmacokinetic studies.
• Deuterated reference compound for quantitative NMR (qNMR) spectroscopy.
• Tracer compound in metabolic pathway research and environmental fate studies.
• Critical reagent in the development and validation of analytical methods for regulatory compliance (e.g., FDA, EMA).
• Precursor for the synthesis of other deuterium-labeled fine chemicals and active pharmaceutical ingredients (APIs).
• Use in stable isotope dilution assays to ensure high accuracy in complex matrix analysis.

Basic Information

Product Name	Phenoxy-D5-Acetic Acid
CAS No.	154492-74-7
Molecular Formula	C8D5HO3
Molecular Weight	157.17 g/mol
Synonyms	(2,3,4,5,6-Pentadeuteriophenoxy)acetic Acid; Phenoxyacetic-d5 Acid; Deuterated Phenoxyacetic Acid; D5-Phenoxyacetic Acid; Phenoxyacetic Acid-d5; (Ring-D5)Phenoxyacetic Acid; 2-(2,3,4,5,6-Pentadeuteriophenoxy)acetic Acid
EINECS	Contact for details

Quality Control

Our Phenoxy-D5-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity (≥98 atom % D) and chemical purity (≥95%). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (by difference)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.