Description

1H-Indole-2-Propanoic Acid, 1-[(4-Chlorophenyl)Methyl]-3-[(1,1-Dimethylethyl)Thio]-5-Methoxy-Ethyl Ester is a sophisticated indole derivative, a key structural motif in medicinal chemistry and advanced organic synthesis. This compound matters as a high-value pharmaceutical intermediate or research chemical, offering a versatile scaffold for developing novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or inflammatory pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new-generation pesticides or plant growth regulators.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Biochemical Probe: Utilized in academic and industrial research to study biological processes and enzyme interactions.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1H-Indole-2-Propanoic Acid, 1-[(4-Chlorophenyl)Methyl]-3-[(1,1-Dimethylethyl)Thio]-5-Methoxy-Ethyl Ester
CAS No.	154325-76-5
Molecular Formula	C25H30ClNO3S
Molecular Weight	460.03 g/mol
Synonyms	1-[(4-Chlorophenyl)methyl]-3-(tert-butylthio)-5-methoxy-1H-indole-2-propanoic acid ethyl ester; Ethyl 1-[(4-chlorophenyl)methyl]-3-(tert-butylthio)-5-methoxy-1H-indole-2-propanoate; 3-(tert-Butylthio)-1-(4-chlorobenzyl)-5-methoxyindole-2-propionic Acid Ethyl Ester; 1-(4-Chlorobenzyl)-3-(tert-butylthio)-5-methoxyindole-2-propanoic Acid Ethyl Ester; 154325-76-5; tert-Butyl 3-[1-(4-chlorobenzyl)-5-methoxy-2-(2-ethoxy-2-oxoethyl)-1H-indol-3-yl]sulfide; 1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-5-methoxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Propanoic Acid derivative is manufactured under strict quality management systems. We provide material with typical purities ≥95% (by HPLC), tailored to meet specific R&D or process requirements. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Our quality commitment ensures consistency and reliability for your critical synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Single impurity ≤ 1.0%; Total impurities ≤ 5.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.