Description

H-Tyr-D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide . Hcl is a specialized chiral amino acid derivative and a key building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceutical agents and bioactive peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, peptide synthesis, and the development of enzyme inhibitors or receptor modulators.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new therapeutic compounds, including potential central nervous system (CNS) agents.
• Peptide Chemistry: Used as a non-natural amino acid analog for the synthesis of modified peptides with enhanced stability or specific biological activity.
• Medicinal Chemistry Research: Serves as a scaffold or precursor in structure-activity relationship (SAR) studies for drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme mechanisms or receptor-ligand interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in stereoselective synthesis routes.

Basic Information

Product Name	H-Tyr-D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide . Hcl
CAS No.	154265-38-0
Molecular Formula	C19H21N3O3 · HCl
Molecular Weight	367.85 g/mol (Free base: 331.39 g/mol)
Synonyms	D-Tic-Tyr-NH2 hydrochloride; H-D-Tic-Tyr-NH2 · HCl; (R)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide hydrochloride; Tyr-D-Tic-NH2 HCl; D-Tic-L-Tyr-NH2 hydrochloride; TYR-D-TIC-NH2 HCL; 154265-38-0
EINECS	Contact for details

Quality Control

Our H-Tyr-D-1,2,3,4-Tetrahydroisoquinoline-3-Carboxamide . Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.