Description

Sibenadet is a selective β-2 adrenoceptor agonist with significant research and pharmaceutical development interest. This compound matters for its potential role in modulating respiratory and inflammatory pathways, offering a targeted mechanism of action. It is primarily needed by pharmaceutical R&D teams, academic researchers, and contract manufacturing organizations (CMOs) focused on developing novel therapeutics for respiratory conditions.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting β-2 adrenergic receptors.
• Respiratory Research: Used in preclinical and clinical research to study bronchial dilation and the treatment of conditions like asthma and chronic obstructive pulmonary disease (COPD).
• Biochemical Assay Standard: Employed as a reference standard in high-throughput screening (HTS) and in vitro pharmacological studies to evaluate receptor binding affinity and functional activity.
• Mechanism of Action Studies: A critical tool for investigating the signaling pathways and downstream effects of β-2 adrenoceptor activation in various cell types.
• Formulation Development: Utilized in the development and stability testing of novel drug delivery systems, such as inhalers or controlled-release formulations.

Basic Information

Product Name	Sibenadet
CAS No.	154189-40-9
Molecular Formula	C19H24N2O3S
Molecular Weight	360.47 g/mol
Synonyms	Viozan; (R,R)-5-(2-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)propyl)-1,3-benzodioxole-2,2-dicarboxylic acid disodium salt; SB 234551; Sibenadet hydrochloride; AR-C68397AA
EINECS	Contact for details

Quality Control

Our Sibenadet is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.