Description

Pentanedioic-D6 Acid CAS NO 154184-99-3 is a deuterium-labeled analog of glutaric acid, where six hydrogen atoms are replaced by the stable isotope deuterium. This high-purity labeled compound is essential for applications requiring precise internal standards in quantitative mass spectrometry and NMR spectroscopy. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry industries for method development and accurate metabolite tracking.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical deuterated internal standard in LC-MS and GC-MS for the accurate quantification of glutaric acid and related metabolites in complex biological matrices.
• Metabolomics & Biomarker Research: Used in stable isotope dilution assays to study metabolic pathways, inborn errors of metabolism (e.g., glutaric aciduria), and to discover reliable biomarkers.
• Pharmaceutical Development: Employed in pharmacokinetic (PK) and pharmacodynamic (PD) studies for tracing drug metabolites, ensuring regulatory compliance and data integrity in drug development dossiers.
• Environmental & Food Safety Testing: Acts as a reference standard in analytical methods for detecting organic acid contaminants or residues, enhancing method accuracy and reproducibility.
• NMR Spectroscopy Solvent: Used as a chemical shift reference or for signal locking in deuterated solvents for high-resolution NMR studies.
• Chemical Synthesis Intermediate: Functions as a labeled building block for the synthesis of more complex deuterated compounds for research and diagnostic purposes.

Basic Information

Product Name	Pentanedioic-D6 Acid
CAS No.	154184-99-3
Molecular Formula	C5D6O4
Molecular Weight	136.14 g/mol
Synonyms	Glutaric Acid-d6; [2H6]-Glutaric Acid; Pentanedioic-2,2,3,3,4,4-d6 Acid; 1,5-Pentanedioic-d6 Acid; Deuterated Glutaric Acid; Glutaric Acid (D6); 1,3-Propanedicarboxylic-d6 Acid; (2,2,3,3,4,4-2H6)Glutaric Acid
EINECS	Contact for details

Quality Control

Our Pentanedioic-D6 Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) detailing assay, isotopic enrichment, and impurity profiles to ensure it meets the exacting standards required for research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to handle the material under a dry inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.