Description

3-Bromoacetyl-2-Thiophenesulfonamide is a specialized organosulfur building block featuring both a reactive bromoacetyl group and a sulfonamide moiety. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists working on novel active ingredients, particularly in the development of enzyme inhibitors and receptor modulators.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential therapeutic agents, including kinase inhibitors and other enzyme-targeted drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the thiophene scaffold.
• Chemical Biology Probes: Serves as a precursor for activity-based probes (ABPs) or affinity labels to study protein function and interactions.
• Material Science: Potential monomer or cross-linking agent for creating specialized polymers with unique electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Bromoacetyl-2-Thiophenesulfonamide
CAS No.	154127-28-3
Molecular Formula	C6H6BrNO3S2
Molecular Weight	284.15 g/mol
Synonyms	2-Thiophenesulfonamide, 3-(bromoacetyl)-; 3-(Bromoacetyl)thiophene-2-sulfonamide; 1-(2-Sulfamoylthiophen-3-yl)-2-bromoethan-1-one; 3-Bromoacetylthiophene-2-sulfonamide; Bromoacetyl Thiophenesulfonamide; 154127-28-3; 3-Bromoacetyl-2-thiophenesulphonamide
EINECS	Contact for details

Quality Control

Our 3-Bromoacetyl-2-Thiophenesulfonamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.