Description

1-Azabicyclo[2.2.1]Heptane-4-Methanol is a specialized bicyclic amine derivative, serving as a high-value pharmaceutical intermediate and chiral building block. Its constrained, nitrogen-containing bicyclic structure makes it a critical precursor for synthesizing complex molecules in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of central nervous system (CNS) active drugs, including potential analgesics and neurological agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its unique stereochemistry.
• Ligand and Catalyst Preparation: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.
• Fine Chemical Production: A building block for other high-value, complex specialty chemicals requiring a rigid amine scaffold.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane-4-Methanol
CAS No.	154044-10-7
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	4-(Hydroxymethyl)-1-azabicyclo[2.2.1]heptane; 1-Azabicyclo[2.2.1]heptane-4-methanol; 4-Hydroxymethyl-1-azabicyclo[2.2.1]heptane; (1R,4S)-1-Azabicyclo[2.2.1]heptane-4-methanol; (1S,4R)-1-Azabicyclo[2.2.1]heptane-4-methanol; Endo-1-Azabicyclo[2.2.1]heptane-4-methanol; Bicyclic amino alcohol
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptane-4-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.