Description

6H-(1,2,4)Triazolo(4,3-A)(1,5)Benzodiazepine, 8-Chloro-5-(4-Methyl-1-Piperazinyl)-6-Phenyl- is a high-purity, complex heterocyclic compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological reference standard and a key synthetic intermediate for exploring novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and contract research organizations (CROs) engaged in the discovery of new chemical entities.

Application

• Pharmaceutical Reference Standard: Used for method development, validation, and quality control in analytical laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a crucial building block in the multi-step synthesis of potential drug candidates.
• Biochemical Research: Employed in in vitro studies to investigate receptor binding affinity and pharmacological activity.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the efficient production of target molecules.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	6H-(1,2,4)Triazolo(4,3-A)(1,5)Benzodiazepine, 8-Chloro-5-(4-Methyl-1-Piperazinyl)-6-Phenyl-
CAS No.	153901-53-2
Molecular Formula	C21H21ClN6
Molecular Weight	392.89 g/mol
Synonyms	8-Chloro-5-(4-methylpiperazin-1-yl)-6-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; 153901-53-2; 6H-[1,2,4]Triazolo[4,3-a][1,5]benzodiazepine, 8-chloro-5-(4-methyl-1-piperazinyl)-6-phenyl-; 8-Chloro-6-phenyl-5-(4-methyl-1-piperazinyl)-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.