Description

(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Methanol CAS NO 153758-56-6 is a versatile heterocyclic building block and chiral intermediate of significant interest in advanced organic synthesis. Its core structure makes it a valuable precursor for the development of pharmacologically active compounds, particularly in central nervous system (CNS) research. This high-purity intermediate is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries seeking to create novel molecular entities.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, especially in neurological and psychiatric disorder research.
• Organic Synthesis Reagent: Used in asymmetric synthesis and as a precursor for more complex tetrahydroisoquinoline derivatives.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands used in catalytic asymmetric reactions.
• Agrochemical Research: Intermediate in the development of new active ingredients with specific biological activity.
• Academic & Industrial R&D: Fundamental compound for methodological studies and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	(1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Methanol
CAS No.	153758-56-6
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	1,2,3,4-Tetrahydro-1-isoquinolinemethanol; 1-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline; (1,2,3,4-Tetrahydroisoquinolin-1-yl)methanol; 1,2,3,4-Tetrahydroisoquinoline-1-methanol; THIQ-1-Methanol; 1-(Hydroxymethyl)-THIQ
EINECS	Contact for details

Quality Control

Our (1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis and purification to meet specific client specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.