Description

Methyl 3-(1,3-Dioxoisoindolin-2-Yl)-2-Hydroxypropanoate is a specialized organic compound featuring a phthalimide-protected amino acid ester structure, making it a valuable synthetic intermediate. Its core value lies in enabling the controlled synthesis and modification of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This high-purity building block is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce specific functional groups with precision.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring phthalimide-protected amino acid motifs.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and mimetics for therapeutic applications.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides with specific bioactive properties.
• Chemical Biology Probes: Employed in the creation of labeled compounds and probes for studying biological mechanisms and enzyme interactions.
• Polymer Modification: Can be utilized to introduce functional handles into polymer chains for creating specialty materials with tailored properties.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	Methyl 3-(1,3-Dioxoisoindolin-2-Yl)-2-Hydroxypropanoate
CAS No.	153744-36-6
Molecular Formula	C12H11NO5
Molecular Weight	249.22 g/mol
Synonyms	2-Hydroxy-3-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid methyl ester; Methyl 2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propanoate; N-(Methoxycarbonylmethyl)phthalimide; Phthalimidopropionic acid methyl ester; 2-(Methoxycarbonyl)-2-hydroxyethylphthalimide; 153744-36-6; Methyl 3-phthalimido-2-hydroxypropionate
EINECS	Contact for details

Quality Control

Our Methyl 3-(1,3-Dioxoisoindolin-2-Yl)-2-Hydroxypropanoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal standards. For custom synthesis or specific purity requirements (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.