Description

Methyl 3-(1,3-Dioxo-2,3-Dihydro-1H-Isoindol-2-Yl)-2-Oxopropanoate CAS NO 153646-24-3 is a specialized organic compound featuring a phthalimide moiety linked to a methyl oxopropanoate ester. This structure makes it a valuable high-purity building block and key intermediate for advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules. Its reliable quality and consistent supply are critical for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing heterocyclic or imide-based structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where its specific functional groups enable targeted activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex organic molecules, including natural product analogs and novel materials.
• Peptidomimetic Research: Acts as a scaffold or protecting group analog in the development of peptide-like compounds for therapeutic applications.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.

Basic Information

Item	Detail
Product Name	Methyl 3-(1,3-Dioxo-2,3-Dihydro-1H-Isoindol-2-Yl)-2-Oxopropanoate
CAS No.	153646-24-3
Molecular Formula	C12H9NO5
Molecular Weight	247.20 g/mol
Synonyms	2-(2-Methoxy-2-oxoacetyl)-1H-isoindole-1,3(2H)-dione; Methyl 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-2-oxoacetate; 2-(Methoxyoxoacetyl)phthalimide; N-(Methoxyoxoacetyl)phthalimide; Methyl (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)oxoacetate; Methyl 2-(1,3-dioxoisoindolin-2-yl)-2-oxoacetate; 153646-24-3
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(1,3-Dioxo-2,3-Dihydro-1H-Isoindol-2-Yl)-2-Oxopropanoate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and structural identity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality systems are designed to support cGMP-compliant applications where traceability and documentation are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.