Description

5-Ethyl 1-Isobutyl 6-(Trimethylsilyl)Indole-1,5-Dicarboxylate is a sophisticated, multi-functional indole derivative characterized by its unique silyl-protected carboxylate structure. This compound matters as a high-value advanced pharmaceutical intermediate and a versatile building block for complex organic synthesis, offering chemists a protected handle for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its complex indole core.
• Material Science Precursor: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Organic Synthesis Reagent: A versatile synthon for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Ligand and Catalyst Development: Potential use in creating novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Ethyl 1-Isobutyl 6-(Trimethylsilyl)Indole-1,5-Dicarboxylate
CAS No.	153602-84-7
Molecular Formula	C21H31NO4Si
Molecular Weight	389.57 g/mol
Synonyms	1-Isobutyl 5-ethyl 6-(trimethylsilyl)-1H-indole-1,5-dicarboxylate; 6-(Trimethylsilyl)-1H-indole-1,5-dicarboxylic acid 1-isobutyl 5-ethyl ester; 5-Ethyl 1-isobutyl 6-(trimethylsilyl)-1H-indole-1,5-dicarboxylate; TMS-Protected Indole Dicarboxylate; Ethyl Isobutyl 6-TMS-Indole-1,5-Dicarboxylate; 153602-84-7; 6-Trimethylsilyl Indole Dicarboxylate Ester
EINECS	Contact for details

Quality Control

Our 5-Ethyl 1-Isobutyl 6-(Trimethylsilyl)Indole-1,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development projects with material produced under cGMP guidelines upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.