Description

17-(Cyclopropylmethyl)-7-Benzyl-4,5-Epoxy-3,14-Dihydroxymorphinan-6-One is a high-purity, complex morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical characterization of novel therapeutic agents targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) who require precise and reliable chemical building blocks.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new opioid receptor modulators and other CNS-active compounds.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in pharmaceutical manufacturing.
• Biochemical Research: Employed in receptor binding assays and pharmacological studies to investigate structure-activity relationships (SAR).
• Process Chemistry: Serves as a starting material or intermediate in scale-up and optimization of API synthesis routes.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and neuropharmacology projects.

Basic Information

Product Name	17-(Cyclopropylmethyl)-7-Benzyl-4,5-Epoxy-3,14-Dihydroxymorphinan-6-One
CAS No.	153567-11-4
Molecular Formula	C28H29NO4
Molecular Weight	443.54 g/mol
Synonyms	7-Benzyl-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one; 17-Cyclopropylmethyl-7-benzyl-4,5α-epoxy-3,14β-dihydroxymorphinan-6-one; 153567-11-4; 7-Benzyl analog of Buprenorphine; Nor-buprenorphine benzyl derivative
EINECS	Contact for details

Quality Control

Every batch of 17-(Cyclopropylmethyl)-7-Benzyl-4,5-Epoxy-3,14-Dihydroxymorphinan-6-One is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC purity, identity confirmation (IR, NMR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.