Description

1,4-Benzene-D4-Diamine is a deuterated analog of para-phenylenediamine, where four hydrogen atoms are replaced with deuterium, a stable hydrogen isotope. This isotopic labeling is critical for applications requiring precise molecular tracking and reduced metabolic interference. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled intermediates.

Application

• Pharmaceutical Research & Development: Used as a deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantitative bioanalysis.
• Metabolic Pathway Studies: Serves as a tracer in drug metabolism and pharmacokinetics (DMPK) studies to elucidate metabolic pathways and identify metabolites.
• Deuterated Active Pharmaceutical Ingredient (API) Synthesis: A key precursor for synthesizing deuterated drug candidates, which can offer improved metabolic stability and pharmacokinetic profiles.
• Polymer & Material Science: Employed in the synthesis of specialized deuterated polymers for neutron scattering studies to investigate polymer structure and dynamics.
• Agrochemical Research: Used in the development and analysis of deuterated pesticides and herbicides to study environmental fate and degradation.
• NMR Spectroscopy: Acts as a useful reagent or intermediate in Nuclear Magnetic Resonance (NMR) spectroscopy, benefiting from the distinct magnetic properties of deuterium.

Basic Information

Product Name	1,4-Benzene-D4-Diamine
CAS No.	153200-72-7
Molecular Formula	C6D4(NH2)2
Molecular Weight	116.17 g/mol
Synonyms	1,4-Diaminobenzene-d4; p-Phenylenediamine-d4; p-Aminoaniline-d4; 1,4-Diamino-2,3,5,6-tetradeuteriobenzene; 1,4-Benzenediamine-d4; Deuteronated PPD; PPD-d4; Benzene-1,4-diamine-d4
EINECS	Contact for details

Quality Control

Our 1,4-Benzene-D4-Diamine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including NMR (¹H, ²H, ¹³C) and HPLC analysis, to confirm isotopic purity (D-enrichment >98 atom % D) and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to light beige crystalline powder
Identification (NMR)	Conforms to structure
Deuterium Enrichment (NMR)	≥ 98 atom % D
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.