Description

6-Fluoro-3-(Piperidin-4-Yl)-1H-Indazole Hydrochloride is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the research and development of novel bioactive molecules, particularly in the field of kinase inhibition. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of targeted therapeutics. The product is supplied as a high-quality salt form to ensure stability and handling consistency for critical process chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a scaffold or reference standard in structure-activity relationship (SAR) studies and high-throughput screening.
• API Development: Serves as a building block in the development and scale-up of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trials.
• Chemical Synthesis: Employed in medicinal chemistry for the construction of complex heterocyclic compounds with potential therapeutic activity.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	6-Fluoro-3-(Piperidin-4-Yl)-1H-Indazole Hydrochloride
CAS No.	153025-27-5
Molecular Formula	C12H15ClFN3
Molecular Weight	255.72 g/mol
Synonyms	6-Fluoro-3-(4-piperidinyl)-1H-indazole hydrochloride; 1H-Indazole, 6-fluoro-3-(4-piperidinyl)-, hydrochloride; 3-(Piperidin-4-yl)-6-fluoro-1H-indazole hydrochloride; 6-Fluoro-3-piperidin-4-yl-1H-indazole HCl; 153025-27-5; 6-Fluoro-3-(4-piperidyl)-1H-indazole hydrochloride; 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indazole hydrochloride (related precursor)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-(Piperidin-4-Yl)-1H-Indazole Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.