Description

2-[(3-Methyloxetan-3-Yl)Methyl]Isoindole-1,3-Dione is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique oxetane and phthalimide functionalities enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its structural motifs for enhanced biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the creation of novel ligands that can modulate catalytic activity in asymmetric synthesis.
• Proteolysis-Targeting Chimera (PROTAC) Linker: Investigated for use in the design of PROTAC molecules, where its structure can contribute to the linker moiety connecting an E3 ligase ligand to a protein-of-interest ligand.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and protein-protein interactions within biological systems.

Basic Information

Product Name	2-[(3-Methyloxetan-3-Yl)Methyl]Isoindole-1,3-Dione
CAS No.	153004-74-1
Molecular Formula	C13H13NO3
Molecular Weight	231.25 g/mol
Synonyms	3-[(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3-methyloxetane; 3-Methyl-3-(phthalimidomethyl)oxetane; N-(3-Methyloxetan-3-ylmethyl)phthalimide; 2-((3-Methyloxetan-3-yl)methyl)isoindoline-1,3-dione; Oxetane, 3-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl]-3-methyl-; 153004-74-1; 3-Methyl-3-phthalimidomethyloxetane
EINECS	Contact for details

Quality Control

Our 2-[(3-Methyloxetan-3-Yl)Methyl]Isoindole-1,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up activities. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.