Description

Diosmetin 3-o-β-D-Glucuronide is a specific flavonoid glucuronide conjugate, a key metabolite of the natural flavone diosmetin. This high-purity reference standard is essential for analytical research, method development, and quality control in pharmaceutical and nutraceutical development. It is primarily sought by research institutions, analytical laboratories, and manufacturers in the pharmaceutical, dietary supplement, and cosmetic industries for its role in bioavailability, metabolism, and pharmacokinetic studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of diosmetin and its metabolites in drug formulations and biological matrices.
• Bioavailability & Metabolism Research: Critical for studying the absorption, distribution, metabolism, and excretion (ADME) profiles of flavonoid-based drugs and supplements.
• Nutraceutical Quality Control: Serves as an analytical standard to assay and ensure the consistency and potency of diosmetin-containing dietary supplements and herbal extracts.
• Cosmetic Ingredient Analysis: Employed in the development and testing of cosmetic products that utilize flavonoids for their antioxidant and skin-conditioning properties.
• Academic & Clinical Research: A vital tool in preclinical and clinical studies investigating the pharmacological activities and metabolic pathways of flavonoids.

Basic Information

Product Name	Diosmetin 3-o-β-D-Glucuronide
CAS No.	152503-50-9
Molecular Formula	C22H20O12
Molecular Weight	476.39 g/mol
Synonyms	Diosmetin 3-O-β-D-Glucuronide; Diosmetin 3-Glucuronide; 3'-Hydroxy-4',5,7-trimethoxyflavone 3-O-β-D-glucuronide; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-3-yl β-D-glucopyranosiduronic acid; Diosmetin-3-O-glucuronide; Luteolin 3'-methyl ether 3-O-β-D-glucuronide
EINECS	Contact for details

Quality Control

Our Diosmetin 3-o-β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to yellow powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Loss on Drying	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.