Description

3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6-Hydroxy-, Methyl Ester is a high-purity, synthetically derived heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure with both carboxylic ester and phenolic hydroxyl functionalities makes it a versatile intermediate for creating complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical developers for the synthesis of novel active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new therapeutic agents, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used to construct complex isoquinoline-based frameworks for medicinal chemistry and material science applications.
• Agrochemical Research: Serves as a starting material for developing novel crop protection agents and plant growth regulators.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme interactions and biological pathways.
• Fine Chemical Production: Employed in the manufacture of specialty dyes, pigments, and advanced organic materials.

Basic Information

Product Name	3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6-Hydroxy-, Methyl Ester
CAS No.	152495-61-9
Molecular Formula	C11H13NO3
Molecular Weight	207.23 g/mol
Synonyms	Methyl 1,2,3,4-tetrahydro-6-hydroxyisoquinoline-3-carboxylate; 6-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid methyl ester; 1,2,3,4-Tetrahydro-6-hydroxy-3-isoquinolinecarboxylic acid methyl ester; THIQ derivative; Tetrahydroisoquinoline carboxylate ester
EINECS	Contact for details

Quality Control

Our production of 3-Isoquinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-6-Hydroxy-, Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.