Description

Prazepam-D5 is a deuterated analog of the benzodiazepine derivative prazepam, specifically labeled with five deuterium atoms. This stable isotope-labeled compound is an essential reference standard and internal standard for precise analytical quantification in research and quality control laboratories. It is primarily used in the development and validation of sensitive LC-MS/MS and GC-MS methods for pharmacokinetic studies, forensic analysis, and drug metabolism research. The high isotopic purity and chemical stability of Prazepam-D5 ensure reliable and reproducible results in complex biological matrices.

Application

• Internal Standard for Mass Spectrometry: Serves as a critical internal standard for the accurate quantification of prazepam and its metabolites in bioanalytical methods using LC-MS/MS or GC-MS.
• Pharmacokinetic and Metabolism Research: Used in drug development studies to track absorption, distribution, metabolism, and excretion (ADME) profiles with high precision.
• Forensic and Clinical Toxicology: Enables reliable identification and quantification of prazepam in forensic investigations and clinical toxicology screenings.
• Pharmaceutical Quality Control: Acts as a reference standard for assay and impurity testing of prazepam in pharmaceutical formulations.
• Isotope Dilution Analysis: Employed in advanced analytical techniques to improve accuracy and compensate for matrix effects and instrument variability.
• Research Chemical: Utilized in academic and industrial research focused on benzodiazepine chemistry, neuropharmacology, and analytical method development.

Basic Information

Product Name	Prazepam-D5
CAS No.	152477-89-9
Molecular Formula	C19H12D5ClN2O2
Molecular Weight	329.81 g/mol
Synonyms	7-Chloro-1-(cyclopropylmethyl)-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one-d5; Desmethyldiazepam Derivative-d5; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-, d5-; Prazepam (phenyl-d5); Prazepam-d5; LS-511-d5; Centrax-d5
EINECS	Contact for details

Quality Control

Every batch of Prazepam-D5 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, supported by comprehensive analytical data including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic enrichment, and absence of critical impurities. Our quality commitment ensures the material meets the stringent requirements for use as a certified reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.