Description

4-Hydroxybenzaldehyde-Carbonyl-13C is a stable isotope-labeled derivative of 4-hydroxybenzaldehyde, where the carbonyl carbon atom is replaced with the carbon-13 (13C) isotope. This compound is a critical tool for advanced analytical research, providing an internal standard for precise quantification and metabolic pathway tracing using techniques like mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for drug metabolism studies, proteomics, and the development of novel diagnostic agents.

Application

• Internal Standard for Quantitative Mass Spectrometry (MS): Used as a reference compound for the accurate quantification of 4-hydroxybenzaldehyde and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Enables the study of biochemical pathways and drug metabolism in pharmacokinetic and pharmacodynamic research.
• NMR Spectroscopy Studies: Serves as a labeled probe for structural elucidation and dynamic studies of molecular interactions.
• Proteomics and Biomarker Research: Facilitates the labeling and detection of proteins and small molecules in discovery workflows.
• Synthesis of Labeled Pharmaceutical Intermediates: Acts as a key building block for the synthesis of 13C-labeled drug candidates and active pharmaceutical ingredients (APIs).
• Environmental and Food Safety Analysis: Employed in isotope dilution methods for the sensitive detection of phenolic aldehydes in environmental and food samples.

Basic Information

Product Name	4-Hydroxybenzaldehyde-Carbonyl-13C
CAS No.	152404-52-9
Molecular Formula	C7H613CO2
Molecular Weight	123.11 g/mol (for 13C1 labeled)
Synonyms	p-Hydroxybenzaldehyde-13C (carbonyl); 4-Formylphenol-13C; 4-Hydroxybenzenecarboxaldehyde-13C; PHBA-13C; (4-Hydroxyphenyl)methanone-13C; 1-13C-4-Hydroxybenzaldehyde; 4-Hydroxybenzaldehyde-1-13C
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxybenzaldehyde-Carbonyl-13C is produced and analyzed under strict quality management protocols to ensure the highest isotopic and chemical purity for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and provide detailed data on isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom % 13C
Chemical Purity (HPLC)	≥ 98.0%
Melting Point	115 - 118 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.