Description

Methyl 3-tert-Butyl-1H-Pyrazole-5-Carboxylate is a high-purity pyrazole derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with specific biological and chemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a core building block in the research and production of modern pesticides, herbicides, and fungicides, contributing to new modes of action.
• Ligand and Catalyst Development: Used in the preparation of specialized pyrazole-based ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers where the pyrazole moiety imparts specific electronic or structural characteristics.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 3-tert-Butyl-1H-Pyrazole-5-Carboxylate
CAS No.	152307-84-1
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	Methyl 5-tert-butyl-1H-pyrazole-3-carboxylate; 3-tert-Butyl-1H-pyrazole-5-carboxylic acid methyl ester; 1H-Pyrazole-5-carboxylic acid, 3-(1,1-dimethylethyl)-, methyl ester; Methyl 3-(tert-butyl)-1H-pyrazole-5-carboxylate; 5-(tert-Butyl)-1H-pyrazole-3-carboxylic acid methyl ester; 3-tert-Butyl-1H-pyrazole-5-carboxylic acid methyl ester; Methyl 5-(tert-butyl)-1H-pyrazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-tert-Butyl-1H-Pyrazole-5-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.