Description

(S)-(+)-4-(1H-Indol-3-Ylmethyl)-2-Oxazolinone is a chiral oxazolinone derivative featuring an indole moiety, serving as a high-value synthetic intermediate. This compound matters for its role in the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active compounds and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereocontrolled reactions to introduce specific three-dimensional configurations into target molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Development: Intermediate in the research and synthesis of novel, chiral active ingredients for crop protection.
• Academic & Institutional Research: Serves as a specialized reagent in university and institutional labs for methodological development in organic and medicinal chemistry.
• Fine Chemical Production: Used in the custom synthesis of complex, high-purity specialty chemicals for various advanced material applications.

Basic Information

Item	Detail
Product Name	(S)-(+)-4-(1H-Indol-3-Ylmethyl)-2-Oxazolinone
CAS No.	152153-01-0
Molecular Formula	C₁₂H₁₀N₂O₂
Molecular Weight	214.22 g/mol
Synonyms	(S)-4-(1H-Indol-3-ylmethyl)-2-oxazolidinone; (S)-(+)-4-(Indol-3-ylmethyl)-2-oxazolidinone; (S)-4-(Indol-3-ylmethyl)oxazolidin-2-one; (S)-4-(1H-Indol-3-ylmethyl)-1,3-oxazolidin-2-one; (S)-4-(3-Indolylmethyl)-2-oxazolidinone; (S)-Indole-3-oxazolidinone derivative; (S)-IOZ; (S)-4-(Indol-3-ylmethyl)oxazolidinone
EINECS	Contact for details

Quality Control

Our (S)-(+)-4-(1H-Indol-3-Ylmethyl)-2-Oxazolinone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.