Description

o-Toluidine-D3 (Methyl-D3) is a deuterated isotopologue of o-toluidine, where three hydrogen atoms on the methyl group are replaced with deuterium. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and precision. It is a critical material for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing industries, where precise measurement of o-toluidine or its metabolites is required.

Application

• Internal Standard for LC-MS/MS: Primary application for the accurate quantification of o-toluidine in complex biological or environmental matrices.
• Pharmaceutical Metabolism Studies: Used in pharmacokinetic and drug metabolism research to track and quantify drug-derived compounds.
• Environmental Analysis: Enables precise monitoring of o-toluidine as a potential industrial pollutant in water and soil samples.
• Toxicological Research: Facilitates studies on the absorption, distribution, and excretion of this aromatic amine.
• Chemical Synthesis Intermediate: Serves as a labeled building block for the synthesis of more complex deuterated molecules.
• Quality Control & Method Development: Critical for developing and validating robust analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).

Basic Information

Product Name	o-Toluidine-D3 (Methyl-D3)
CAS No.	151985-13-6
Molecular Formula	C7H6D3N
Molecular Weight	110.17 g/mol
Synonyms	2-Methylaniline-d3; 2-Aminotoluene-d3; 2-Methylbenzenamine-d3; o-Methylaniline-d3; 1-Amino-2-methylbenzene-d3; (2-Methylphenyl)amine-d3; 2-Toluidine-d3; o-Tolylamine-d3
EINECS	Contact for details

Quality Control

Every batch of o-Toluidine-D3 (Methyl-D3) is produced and analyzed under strict quality management systems to ensure the high chemical purity and isotopic enrichment required for analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specifications such as isotopic purity (D-content), chemical purity (by GC or HPLC), and identity confirmation (by NMR/MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.