Description

(6R,7S)-2-Boc-2-Aza-Bicyclo[2.2.1]Hept-5-En-3-One is a high-purity, advanced pharmaceutical intermediate featuring a unique bicyclic lactam structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel protease inhibitors and other therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in cutting-edge drug discovery and process chemistry.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block for the production of complex pharmaceutical molecules, especially those targeting viral proteases.
• Protease Inhibitor Development: Used in the research and manufacturing of novel protease inhibitor drugs for treating conditions like hepatitis C and HIV.
• Chiral Pool Synthesis: Its defined stereochemistry makes it a valuable starting material for the synthesis of other enantiomerically pure compounds.
• Peptidomimetic Research: Employed in medicinal chemistry to create peptide-like molecules with enhanced metabolic stability and bioavailability.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial-scale production of target molecules.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists exploring new methodologies and complex molecular architectures.

Basic Information

Product Name	(6R,7S)-2-Boc-2-Aza-Bicyclo[2.2.1]Hept-5-En-3-One
CAS No.	151792-53-9
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(3aR,4S,7R,7aS)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[2.2.1]hept-5-ene-3,7a(1H)-dione; 2-Boc-2-azabicyclo[2.2.1]hept-5-en-3-one; tert-Butyl (1S,4R)-3-oxo-2-azabicyclo[2.2.1]hept-5-ene-2-carboxylate; 2-Aza-bicyclo[2.2.1]hept-5-ene-3-one, 2-Boc-protected; Bicyclic Lactam Boc Derivative; 151792-53-9; Boc-Aze-Norbornene Lactam
EINECS	Contact for details

Quality Control

Our (6R,7S)-2-Boc-2-Aza-Bicyclo[2.2.1]Hept-5-En-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.