Description

3-Phenyl-5-(2-Thienylmethylene)-2-(2,3,4,6-Tetra-o-Acetylglucopyranosyl)-2-Thiohydantoin is a sophisticated heterocyclic compound that serves as a key synthetic intermediate in advanced organic and medicinal chemistry research. Its complex structure, featuring a thiohydantoin core linked to acetylated sugar and aromatic moieties, makes it a valuable scaffold for developing novel bioactive molecules. This compound is primarily utilized by research scientists and process development chemists in the pharmaceutical and biotechnology sectors for the synthesis of potential therapeutic agents and for probing structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting metabolic or enzymatic pathways.
• Glycoconjugate Research: Used in the study and development of glycosylated compounds, leveraging its tetra-acetylglucopyranosyl group for carbohydrate-based chemistry.
• Medicinal Chemistry Probe: Acts as a core scaffold for generating compound libraries to investigate biological activity and optimize lead structures.
• Chemical Biology Tool: Employed in studies exploring protein-ligand interactions, especially where thiohydantoin derivatives are known to exhibit binding affinity.
• Academic & R&D Synthesis: A valuable reagent for university and industrial research laboratories focused on heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	3-Phenyl-5-(2-Thienylmethylene)-2-(2,3,4,6-Tetra-o-Acetylglucopyranosyl)-2-Thiohydantoin
CAS No.	151731-16-7
Molecular Formula	C28H28N2O9S2
Molecular Weight	600.66 g/mol
Synonyms	2-Thiohydantoin, 3-phenyl-5-[(2-thienyl)methylene]-2-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thio]-; 2-[(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl)thio]-3-phenyl-5-[(2-thienyl)methylene]-2,4-imidazolidinedione; 3-Phenyl-5-(2-thienylmethylene)-2-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)thio]hydantoin; 2-(2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosylthio)-3-phenyl-5-(2-thienylmethylene)hydantoin; β-D-Glucopyranose, 1,2,3,4-tetraacetate 6-[3-phenyl-5-[(2-thienyl)methylene]-2,4-dioxo-1-imidazolidinyl]thio]-, 1-thio-; CAS 151731-16-7
EINECS	Contact for details

Quality Control

Our 3-Phenyl-5-(2-Thienylmethylene)-2-(2,3,4,6-Tetra-o-Acetylglucopyranosyl)-2-Thiohydantoin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials undergo comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.