Description

2-Azetidinone,1-(1-Oxo-2-Propenyl)-(9Ci) is a specialized β-lactam derivative, a key structural motif in medicinal chemistry. This compound serves as a versatile and valuable chemical building block for the synthesis of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel β-lactam antibiotics and other bioactive compounds targeting bacterial infections.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems due to its reactive β-lactam ring and acryloyl side chain.
• Protease Inhibitor Development: Acts as a key intermediate in the research and development of enzyme inhibitors, leveraging the β-lactam's affinity for active sites.
• Academic & Institutional Research: Serves as a reagent for studying reaction mechanisms and developing new synthetic methodologies in organic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	2-Azetidinone,1-(1-Oxo-2-Propenyl)-(9Ci)
CAS No.	151586-60-6
Molecular Formula	C6H7NO2
Molecular Weight	125.13 g/mol
Synonyms	1-Acryloylazetidin-2-one; N-Acryloyl-2-azetidinone; 1-(Acryloyl)azetidin-2-one; 2-Azetidinone, 1-acryloyl-; N-Acryloylazetidinone; Azetidin-2-one, 1-acryloyl-; 1-(1-Oxo-2-propenyl)-2-azetidinone; 1-Propenoyl-2-azetidinone
EINECS	Contact for details

Quality Control

Our 2-Azetidinone,1-(1-Oxo-2-Propenyl)-(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.