Description

Iralukast CAS NO 151581-24-7 is a high-purity, synthetic leukotriene receptor antagonist (LTRA) compound. This active pharmaceutical ingredient (API) is critical for research and development in the field of respiratory pharmacology, specifically targeting inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers developing novel therapeutics for asthma and other inflammatory conditions.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key reference standard and building block in the discovery and development of new leukotriene pathway inhibitors.
• Preclinical Studies: Used in in vitro and in vivo models to study anti-inflammatory mechanisms, pharmacokinetics, and efficacy for respiratory diseases.
• Analytical Method Development: Employed as a high-purity standard for developing and validating HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Chemical Synthesis: Acts as an intermediate or precursor for the synthesis of more complex molecules or analogs within medicinal chemistry programs.
• Academic Research: Supports university and institutional research into the biochemistry of leukotrienes and related inflammatory mediators.

Basic Information

Product Name	Iralukast
CAS No.	151581-24-7
Molecular Formula	C31H33N3O6S
Molecular Weight	575.68 g/mol
Synonyms	Iralukast; RG 12525; RG-12525; 4-[4-(4-Phenylbutoxy)benzoylamino]-3-[4-[[[3-(1H-tetrazol-5-yl)phenyl]thio]methyl]phenyl]butanoic Acid; 4-[4-(4-Phenylbutoxy)benzamido]-3-[4-[[[3-(1H-tetrazol-5-yl)phenyl]sulfanyl]methyl]phenyl]butanoic Acid; 4-[4-(4-Phenylbutoxy)benzamido]-3-[4-[[[3-(1H-tetrazol-5-yl)phenyl]thio]methyl]phenyl]butanoic Acid
EINECS	Contact for details

Quality Control

Our Iralukast is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing results from HPLC, NMR, and MS analyses. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.