Description

2-(1-Methyl-1H-Indol-3-Yl)-2-Oxoacetic Acid Methyl Ester is a high-value synthetic intermediate characterized by its indole-based molecular scaffold. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with indole motifs.
• Organic Synthesis: Versatile reagent for constructing complex heterocycles and fused ring systems in academic and industrial laboratories.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials.
• Bioconjugation Chemistry: Used in the development of fluorescent probes and biochemical tools due to its reactive keto-ester group.

Basic Information

Product Name	2-(1-Methyl-1H-Indol-3-Yl)-2-Oxoacetic Acid Methyl Ester
CAS No.	151490-40-3
Molecular Formula	C₁₂H₁₁NO₃
Molecular Weight	217.22 g/mol
Synonyms	Methyl 2-(1-methyl-1H-indol-3-yl)-2-oxoacetate; 2-Oxo-2-(1-methyl-1H-indol-3-yl)acetic acid methyl ester; 1-Methylindole-3-glyoxylic acid methyl ester; Methyl (1-methylindol-3-yl)oxoacetate; 151490-40-3; Methyl 1-methylindol-3-ylglyoxylate; 2-(1-Methylindol-3-yl)-2-oxoacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-(1-Methyl-1H-Indol-3-Yl)-2-Oxoacetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.