Description

(4As,7As)-1-Methyloctahydro-1H-Pyrrolo[3,4-B]Pyridine is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry, identified by CAS NO 151213-45-5. This compound is valued for its role as a sophisticated building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, where precise molecular architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, especially for neurological and psychiatric applications.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing novel nitrogen-containing heterocyclic frameworks.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems requiring specific stereochemical control.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(4As,7As)-1-Methyloctahydro-1H-Pyrrolo[3,4-B]Pyridine
CAS No.	151213-45-5
Molecular Formula	C9H18N2
Molecular Weight	154.25 g/mol
Synonyms	1-Methyloctahydro-1H-pyrrolo[3,4-b]pyridine; (4aR,7aR)-1-Methyloctahydro-1H-pyrrolo[3,4-b]pyridine; (4aR,7aR)-1-Methylhexahydro-1H-pyrrolo[3,4-b]pyridine; (4aR,7aR)-1-Methyloctahydropyrrolo[3,4-b]pyridine; (4aR,7aR)-1-Methyl-4a,5,6,7,8,8a-hexahydro-1H-pyrrolo[3,4-b]pyridine; (4aR,7aR)-1-Methyl-1,4a,5,6,7,8,8a,9-octahydro-pyrrolo[3,4-b]pyridine; (4aR,7aR)-1-Methyl-4a,5,6,7,8,8a-hexahydro-1H,9H-pyrrolo[3,4-b]pyridine
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Quality Control

Our (4As,7As)-1-Methyloctahydro-1H-Pyrrolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.