Description

2,5-Morpholinedione,3-Methyl-6-(1-Methylethyl)-,(3R-Trans)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound with the CAS registry number 150934-01-3. This specialized morpholinedione derivative is valued as a critical chiral building block and intermediate in advanced organic synthesis, where its defined stereochemistry and functional groups enable precise molecular construction. It is primarily required by research and development chemists and process engineers in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and complex target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce complex, functionalized heterocyclic motifs into target molecules.
• Fine Chemical Production: Acts as a precursor in the manufacture of specialized fine chemicals, agrochemicals, and performance materials requiring high structural fidelity.
• Academic & Industrial Research: Employed in methodological development and exploratory chemistry within R&D laboratories for creating new chemical entities.
• Process Chemistry: Used in scale-up and optimization studies for the development of efficient and cost-effective synthetic routes to complex molecules.

Basic Information

Product Name	2,5-Morpholinedione,3-Methyl-6-(1-Methylethyl)-,(3R-Trans)-(9Ci)
CAS No.	150934-01-3
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(3R,6S)-3-Methyl-6-(propan-2-yl)morpholine-2,5-dione; (3R-trans)-3-Methyl-6-(1-methylethyl)-2,5-morpholinedione; 3-Methyl-6-isopropyl-2,5-morpholinedione (stereospecific); (3R,6S)-3-Methyl-6-isopropyl-2,5-diketomorpholine; Stereoisomer of 3-Methyl-6-isopropyl-2,5-morpholinedione; (R,S)-3-Methyl-6-isopropyl-2,5-morpholinedione; 150934-01-3; 2,5-Diketomorpholine derivative
EINECS	Contact for details

Quality Control

Our 2,5-Morpholinedione,3-Methyl-6-(1-Methylethyl)-,(3R-Trans)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.