Description

(1R,3R)-3-Phenylcyclobutanol CAS NO 150639-16-0 is a high-purity chiral cyclobutane derivative, a crucial building block in advanced organic synthesis. Its defined stereochemistry and functional group versatility make it an essential intermediate for creating complex molecules with specific three-dimensional architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Research: Used in the development of new herbicides and pesticides with enhanced stereospecific activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Material Science: A building block for advanced polymers and liquid crystals where the rigid cyclobutane core imparts specific material properties.
• Academic & Process Chemistry: Employed in methodological studies and scale-up process development for stereoselective synthesis.

Basic Information

Product Name	(1R,3R)-3-Phenylcyclobutanol
CAS No.	150639-16-0
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(1R,3R)-3-Phenylcyclobutan-1-ol; trans-3-Phenylcyclobutanol; (1R-trans)-3-Phenylcyclobutanol; 3-Phenylcyclobutanol (trans-); Cyclobutanol, 3-phenyl-, (1R,3R)-; 150639-16-0; (1R,3R)-3-Phenyl-1-cyclobutanol
EINECS	Contact for details

Quality Control

Our (1R,3R)-3-Phenylcyclobutanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.