Description

(1S,3S)-3-Phenylcyclobutanol CAS NO 150639-15-9 is a high-purity chiral cyclobutane derivative, a valuable building block in advanced organic synthesis. Its defined stereochemistry and functionalized cyclobutane ring make it a critical intermediate for constructing complex molecular architectures with high precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the rigid cyclobutane structure imparts desirable biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of novel polymers and liquid crystals, where the phenylcyclobutanol moiety can influence material properties.
• Academic & Industrial R&D: A versatile scaffold in method development and exploration of new chemical spaces within organic and medicinal chemistry laboratories.

Basic Information

Product Name	(1S,3S)-3-Phenylcyclobutanol
CAS No.	150639-15-9
Molecular Formula	C10H12O
Molecular Weight	148.20 g/mol
Synonyms	(1S,3S)-3-Phenylcyclobutan-1-ol; (1S-cis)-3-Phenylcyclobutanol; cis-3-Phenylcyclobutanol; 3-Phenylcyclobutanol (cis-); 150639-15-9; Cyclobutanol, 3-phenyl-, (1S,3S)-; (1S,3S)-3-Phenyl-1-cyclobutanol
EINECS	Contact for details

Quality Control

Our (1S,3S)-3-Phenylcyclobutanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, NMR, and GC-MS, to ensure identity, purity, and enantiomeric excess meet rigorous standards. Certificates of Analysis (COA) documenting all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.