Description

6-Amino-5-Fluoroindolin-2-One is a high-purity fluorinated indolinone derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its fluorinated indole structure.
• Chemical Biology & Proteomics: Employed as a molecular probe or scaffold for studying enzyme inhibition and protein-ligand interactions.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic electronic materials.
• Academic & Contract Research: Serves as a standard or starting material in university laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.

Basic Information

Product Name	6-Amino-5-Fluoroindolin-2-One
CAS No.	150544-01-7
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	5-Fluoro-6-aminoindolin-2-one; 2H-Indol-2-one, 6-amino-5-fluoro-1,3-dihydro-; 6-Amino-5-fluoro-1,3-dihydro-2H-indol-2-one; 5-Fluoro-6-aminooxindole; 6-Amino-5-fluorooxindole; 150544-01-7; AI3-52779
EINECS	Contact for details

Quality Control

Our 6-Amino-5-Fluoroindolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.